Iris Gratz, member of the ACBN focus program of the University of Salzburg, and colleagues have discovered a population of human immune cells in the blood that appear to have everything in common with infection-fighting T cells isolated from the skin. The findings were published in the journal Science Immunology and were featured on the July cover of the journal. The work challenges current thinking that skin-resident memory T cells are strictly retained in the skin. Iris Gratz and her team, in partnership with Daniel Campbell at the Benaroya Research Institute at Virginia Mason (BRI), and scientists at the University of Pennsylvania and other research institutions, demonstrated that tissue-resident memory T cells can exit skin tissue, enter the blood and circulate throughout the body. These T cells can then relocate into skin at other locations of the body. By studying these T cells in more detail, Gratz and colleagues found that the migration of the T cells likely plays a role in the healing of skin wounds and the ability to recognize and protect against infection. “Once these cells have battled an infectious agent at one site on the skin, they may be able to recognize and fend off infection at other sites and in subsequent encounters,” the researcher said. The discovery of tissue-resident memory in the circulation of healthy individuals greatly facilitates the isolation and study of cutaneous memory T cells from a broadly available human tissue, the blood.
Announcement of ICA Symposium, February 2019
The upcoming ICA Symposium is scheduled for the 4th and 5th of February 2019. It will be organized as a joint symposium between the Doctoral College ICA and the Doctorate School DSP Biomolecules. Please register here for the Symposium as soon as possible, giving titles for presentations when applicable. Registration needs to be finished by January 3rd, 2019. Faculty members please also register, of course you do not need to give details for presentations.
A new homepage for ACBn and DSP BioM goes on-line (the one you are reading).
The fellows have meetings with members of our advisory board and – as full-day retreat – with a colleague from the pharmaceutical industry. The topic of discussion is in both cases how to proceed with career building after the PhD is finished. We note with some satisfaction that still all alumni (by now 6) have decent jobs. The DSP seeks to establish a tradition here!
New DSPB speaker
Michael Waller leaves the University and Albert Duschl becomes the new speaker, with Chiara Cabrele as deputy.
Status of the DSPB
The DSP has at the end of the year 12 fellows and 4 alumni. Of note, all of the alumni have decent jobs!
Work of DSP BioM starts with a Kickoff-Meeting. Our guest of honor is Prof. Dr. Klement Tockner, the President of the FWF.
DSBP application submitted
The application for the DSP Biomolecules – Structure Function and Regulation is submitted to the Rectorate by 19 PIs, under the leadership of Michael Wallner.